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Clindamycin phosphate EP Impurity B

Clindamycin phosphate EP Impurity B

Catalogue No.: VL1030002
CAS No.: 54887-31-9

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Name: Clindamycin phosphate EP Impurity B
Catalogue No. VL1030002
CAS No. 54887-31-9
Molecular Formula C17H33ClN2O8PS
Molecular Weight 490.94
Status In-stock
IUPAC Name Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-1-methylpyrrolidin-2-yl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate) ;
Synonyms Clindamycin B 2-Phosphate
Appearance White solid
Description Clindamycin phosphate EP Impurity B (CAS No: 54887-31-9) or Clindamycin B 2-Phosphate is a metabolite of Clindamycin identified by HPLC. Clindamycin is an antimicrobial agent which is evaluated for infective endocarditis prophylaxis but seldom for other clinical situations, which need antimicrobial intervention. This has been mainly because of its relation with acute pseudomembranous colitis.
References Morozowich, Walter, and Roger G. Williams. “Liquid Chromatography of Clindamycin 2‐Phosphate on Triethylaminoethyl Cellulose.” Journal of Pharmaceutical Sciences, vol. 64, no. 2, Feb. 1975, pp. 313–16, https://doi.org/10.1002/jps.2600640227. ‌Addy, L. D., and M. V. Martin. “Clindamycin and Dentistry.” British Dental Journal, vol. 199, no. 1, July 2005, pp. 23–26, https://doi.org/10.1038/sj.bdj.4812535.

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