| Name: | Clindamycin Phosphate EP Impurity E (free base) |
| Catalogue No. | VL1030009 |
| CAS No. | 18323-44-9 |
| Molecular Formula | C18H33ClN2O5S |
| Molecular Weight | 424.98 g/mol |
| Status | In-Stock |
| IUPAC Name | Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside. |
| Synonyms | Clindamycin BP Impurity E/ Clindamycin Hydrochloride EP Impurity E (free base) |
| Description | Clindamycin Phosphate EP Impurity E (free base) (CAS No: 18323-44-9) or Clindamycin BP Impurity E is a degradation product in Clindamycin. Clindamycin is an antimicrobial agent which is evaluated for infective endocarditis prophylaxis but seldom for other clinical situations, which need antimicrobial intervention. This has been mainly because of its relation with acute pseudomembranous colitis. |
| References | Brown, Leo W. “High-Pressure Liquid Chromatographic Assays for Clindamycin, Clindamycin Phosphate, and Clindamycin Palmitate.” Journal of Pharmaceutical Sciences, vol. 67, no. 9, Sept. 1978, pp. 1254–57, https://doi.org/10.1002/jps.2600670917. |
