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Clindamycin Phosphate EP Impurity E (free base)

Clindamycin Phosphate EP Impurity E (free base)

Catalogue No.: VL1030009
CAS No.: 18323-44-9

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Name: Clindamycin Phosphate EP Impurity E (free base)
Catalogue No. VL1030009
CAS No. 18323-44-9
Molecular Formula C18H33ClN2O5S
Molecular Weight 424.98 g/mol
Status In-Stock
IUPAC Name Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside.
Synonyms Clindamycin BP Impurity E/ Clindamycin Hydrochloride EP Impurity E (free base)
Description Clindamycin Phosphate EP Impurity E (free base) (CAS No: 18323-44-9) or Clindamycin BP Impurity E is a degradation product in Clindamycin. Clindamycin is an antimicrobial agent which is evaluated for infective endocarditis prophylaxis but seldom for other clinical situations, which need antimicrobial intervention. This has been mainly because of its relation with acute pseudomembranous colitis.
References Brown, Leo W. “High-Pressure Liquid Chromatographic Assays for Clindamycin, Clindamycin Phosphate, and Clindamycin Palmitate.” Journal of Pharmaceutical Sciences, vol. 67, no. 9, Sept. 1978, pp. 1254–57, https://doi.org/10.1002/jps.2600670917.

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