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Clindamycin phosphate EP Impurity J

Clindamycin phosphate EP Impurity J

Catalogue No.: VE005870
CAS No.: 1309349-64-1

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Name: Clindamycin phosphate EP Impurity J
Catalogue No. VE005870
CAS No. 1309349-64-1
Molecular Formula C18H32ClN2O8PS
Molecular Weight 502.96
Status In-stock
IUPAC Name methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4-propylidenepyrrolidin-2-yl]carbonyl]amino]-2-O-phosphono-1-thio-L-threo-α-D-galacto-octopyranoside
Synonyms Clindamycin Phosphate Propylidene Analog/ Dehydroclindamycin Phosphate/ Clindamycin Phosphate BP Impurity J
Appearance Off White powder
Description Clindamycin Phosphate EP Impurity J (CAS No: 1309349-64-1) is an adulteration present in Clindamycin. Clindamycin is a potent antibiotic and is often evaluated for the treatment of prosthetic joint infections, as infection prophylaxis in bone cement and chronic osteomyelitis. Clindamycin can stimulate the cell metabolism of human osteoblasts if administered at low concentrations.
References Consultation Documents. apps.who.int/iris/bitstream/handle/10665/331019/DI303-414-476-eng.pdf. Accessed 7 Oct. 2021. Naal, Florian D., et al. “The Effects of Clindamycin on Human Osteoblasts in Vitro.” Archives of Orthopaedic and Trauma Surgery, vol. 128, no. 3, Jan. 2008, pp. 317–23, https://doi.org/10.1007/s00402-007-0561-y.

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