| Name: | Clindamycin phosphate EP Impurity J |
| Catalogue No. | VE005870 |
| CAS No. | 1309349-64-1 |
| Molecular Formula | C18H32ClN2O8PS |
| Molecular Weight | 502.96 |
| Status | In-stock |
| IUPAC Name | methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4-propylidenepyrrolidin-2-yl]carbonyl]amino]-2-O-phosphono-1-thio-L-threo-α-D-galacto-octopyranoside |
| Synonyms | Clindamycin Phosphate Propylidene Analog/ Dehydroclindamycin Phosphate/ Clindamycin Phosphate BP Impurity J |
| Appearance | Off White powder |
| Description | Clindamycin Phosphate EP Impurity J (CAS No: 1309349-64-1) is an adulteration present in Clindamycin. Clindamycin is a potent antibiotic and is often evaluated for the treatment of prosthetic joint infections, as infection prophylaxis in bone cement and chronic osteomyelitis. Clindamycin can stimulate the cell metabolism of human osteoblasts if administered at low concentrations. |
| References | Consultation Documents. apps.who.int/iris/bitstream/handle/10665/331019/DI303-414-476-eng.pdf. Accessed 7 Oct. 2021. Naal, Florian D., et al. “The Effects of Clindamycin on Human Osteoblasts in Vitro.” Archives of Orthopaedic and Trauma Surgery, vol. 128, no. 3, Jan. 2008, pp. 317–23, https://doi.org/10.1007/s00402-007-0561-y. |
