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Clobazam EP Impurity A

Clobazam EP Impurity A

Catalogue No.: VL2500006
CAS No.: 22316-55-8

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Name: Clobazam EP Impurity A
Catalogue No. VL2500006
CAS No. 22316-55-8
Molecular Formula C15H11ClN202
Molecular Weight 286.71
Status In-stock
IUPAC Name 7-chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione;
Synonyms Clobazam Related Compound A
Description Clobazam EP Impurity A (CAS No: 22316-55-8) or 7-chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione is an impurity of the anxiolytic drug, Clobazam. Clobazam is an antiepileptic drug and is evaluated for use in the cure of Lennox-Gastaut Syndrome in patients older than 2 years. Clobazam is also useful as adjunctive therapy for refractory epilepsy and to treat anxiety and some other epileptic syndromes.
References Kumar, Neeraj, et al. “Potential Impurities of Anxiolytic Drug, Clobazam: Identification, Synthesis and Characterization Using HPLC, LC-ESI/MSn and NMR.” Journal of Pharmaceutical and Biomedical Analysis, vol. 137, Apr. 2017, pp. 268–78, https://doi.org/10.1016/j.jpba.2017.01.051. ‌Huddart, Rachel, et al. “PharmGKB Summary.” Pharmacogenetics and Genomics, vol. 28, no. 4, Apr. 2018, pp. 110–15, https://doi.org/10.1097/fpc.0000000000000327.

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