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Clobazam EP Impurity B

Clobazam EP Impurity B

Catalogue No.: VL2500005
CAS No.: 22316-24-1

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Name: Clobazam EP Impurity B
Catalogue No. VL2500005
CAS No. 22316-24-1
Molecular Formula C16H14N2O2
Molecular Weight 266.99
Status In-stock
IUPAC Name 1-methyl-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione
Appearance White solid
Description Clobazam EP Impurity B (CAS No: 22316-24-1) or 1-methyl-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione is a metabolite of Clobazam. Clobazam is a 1,5-benzodiazepine and is proven to have a broad spectrum of antiepileptic activity and is accompanied by low neurotoxicity than the 1,4-benzodiazepines, nitrazepam and clonazepam.
References Florence, Kiruba, et al. “Intranasal Clobazam Delivery in the Treatment of Status Epilepticus.” Journal of Pharmaceutical Sciences, vol. 100, no. 2, Feb. 2011, pp. 692–703, https://doi.org/10.1002/jps.22307. ‌Munn, Robert, and Kevin Farrell. “Open Study of Clobazam in Refractory Epilepsy.” Pediatric Neurology, vol. 9, no. 6, Nov. 1993, pp. 465–69, https://doi.org/10.1016/0887-8994(93)90026-9. ‌

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