| Name: | Clobazam EP Impurity B |
| Catalogue No. | VL2500005 |
| CAS No. | 22316-24-1 |
| Molecular Formula | C16H14N2O2 |
| Molecular Weight | 266.99 |
| Status | In-stock |
| IUPAC Name | 1-methyl-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione |
| Appearance | White solid |
| Description | Clobazam EP Impurity B (CAS No: 22316-24-1) or 1-methyl-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione is a metabolite of Clobazam. Clobazam is a 1,5-benzodiazepine and is proven to have a broad spectrum of antiepileptic activity and is accompanied by low neurotoxicity than the 1,4-benzodiazepines, nitrazepam and clonazepam. |
| References | Florence, Kiruba, et al. “Intranasal Clobazam Delivery in the Treatment of Status Epilepticus.” Journal of Pharmaceutical Sciences, vol. 100, no. 2, Feb. 2011, pp. 692–703, https://doi.org/10.1002/jps.22307. Munn, Robert, and Kevin Farrell. “Open Study of Clobazam in Refractory Epilepsy.” Pediatric Neurology, vol. 9, no. 6, Nov. 1993, pp. 465–69, https://doi.org/10.1016/0887-8994(93)90026-9. |
