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Clobazam EP Impurity D

Clobazam EP Impurity D

Catalogue No.: VL2500001
CAS No.: 2092997-47-0

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Name: Clobazam EP Impurity D
Catalogue No. VL2500001
CAS No. 2092997-47-0
Molecular Formula C18H17ClN2O2
Molecular Weight 328.8
Status In-stock
IUPAC Name 7-chloro-1,3,3-trimethyl-5-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione
Appearance Off White powder
Description Clobazam EP Impurity D (CAS No: 2092997-47-0) or 7-chloro-1,3,3-trimethyl-5-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione is a process impurity of Clobazam. Clobazam is a 1,5-benzodiazepine useful in the therapy of antiepileptic in children and adults. Presently it is majorly evaluated as adjuvant therapy for intractable seizures.
References Kumar, Neeraj, et al. “Potential Impurities of Anxiolytic Drug, Clobazam: Identification, Synthesis and Characterization Using HPLC, LC-ESI/MSn and NMR.” Journal of Pharmaceutical and Biomedical Analysis, vol. 137, Apr. 2017, pp. 268–78, https://doi.org/10.1016/j.jpba.2017.01.051. ‌Theis, Jochen G. W., et al. “Interactions of Clobazam with Conventional Antiepileptics in Children.” Journal of Child Neurology, vol. 12, no. 3, Apr. 1997, pp. 208–13, https://doi.org/10.1177/088307389701200311. ‌

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