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Clonazepam Phthalimido Inhouse Impurity

Clonazepam Phthalimido Inhouse Impurity

Catalogue No.: VE006731
CAS No.: N/A

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Name: Clonazepam Phthalimido Inhouse Impurity
Catalogue No. VE006731
Molecular Formula C23H14ClN3O6
Molecular Weight 463.83
Status In-stock
IUPAC Name N-(2-(2-chlorobenzoyl)-4-nitrophenyl)-2-(1,3-dioxoisoindolin-2-yl)acetamide
Appearance Off-White to Pale Yellow Solid
Description Clonazepam Phthalimido Inhouse Impurity or N-(2-(2-chlorobenzoyl)-4-nitrophenyl)-2-(1,3-dioxoisoindolin-2-yl)acetamide is a Phthalimido derivative of Clonazepam. Clonazepam depresses seizure activity in many animal models of epilepsy and several types of paroxysmal action in the electroencephalogram of patients. Clonazepam usually limits the spread of discharge from a focal lesion but doesn't suppress the primary focus.
References Malminen, O., and P. Kontro. “γ-Aminobutyric Acid and Benzodiazepine Receptors in Cultured Cerebellar Granule Cells: Effects of Taurine and Its Lipophilic Derivatives.” Neuropharmacology, vol. 28, no. 9, Sept. 1989, pp. 907–12, https://doi.org/10.1016/0028-3908(89)90189-5. ‌Koch-Weser, Jan, and Thomas R. Browne. “Clonazepam.” New England Journal of Medicine, vol. 299, no. 15, Oct. 1978, pp. 812–16, https://doi.org/10.1056/nejm197810122991505.

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