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Clonidine 2,6-Dichloroaniline Impurity

Clonidine 2,6-Dichloroaniline Impurity

Catalogue No.: VL281001
CAS No.: 608-31-1

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Name: Clonidine 2,6-Dichloroaniline Impurity
Catalogue No. VL281001
CAS No. 608-31-1
Molecular Formula C₆H₅Cl₂N
Molecular Weight 162.02
Status In-stock
IUPAC Name 2,6-Dichlorobenzenamine
Synonyms Clonidine EP Impurity C
Appearance Off White Crystalline solid
Description Clonidine 2,6-Dichloroaniline Impurity (CAS No: 608-31-1) or 2,6-Dichlorobenzenamine is a pharmaceutical intermediate of Clonidine. Clonidine is an alpha-2 adrenergic agonist which is a significantly potent antinociceptive agent but its use as systemic clonidine for the cure of pain is limited by centrally mediated side effects including sedation, hypotension, and rebound hypertension.
References Lin, Weixiong, et al. “Oxidation of Aniline Aerofloat in Flotation Wastewater by Sodium Hypochlorite Solution.” Environmental Science and Pollution Research, vol. 23, no. 1, Sept. 2015, pp. 785–92, https://doi.org/10.1007/s11356-015-5319-4. ‌Dogrul, Ahmet, and Tayfun I. Uzbay. “Topical Clonidine Antinociception.” Pain, vol. 111, no. 3, Oct. 2004, pp. 385–91, https://doi.org/10.1016/j.pain.2004.07.020.

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