Clonidine 2,6-Dichloroaniline Impurity

Catalogue No.: VL281001
CAS No.: 608-31-1

Name:	Clonidine 2,6-Dichloroaniline Impurity
Catalogue No.	VL281001
CAS No.	608-31-1
Molecular Formula	C₆H₅Cl₂N
Molecular Weight	162.02
Status	In-stock
IUPAC Name	2,6-Dichlorobenzenamine
Synonyms	Clonidine EP Impurity C
Appearance	Off White Crystalline solid
Description	Clonidine 2,6-Dichloroaniline Impurity (CAS No: 608-31-1) or 2,6-Dichlorobenzenamine is a pharmaceutical intermediate of Clonidine. Clonidine is an alpha-2 adrenergic agonist which is a significantly potent antinociceptive agent but its use as systemic clonidine for the cure of pain is limited by centrally mediated side effects including sedation, hypotension, and rebound hypertension.
References	Lin, Weixiong, et al. “Oxidation of Aniline Aerofloat in Flotation Wastewater by Sodium Hypochlorite Solution.” Environmental Science and Pollution Research, vol. 23, no. 1, Sept. 2015, pp. 785–92, https://doi.org/10.1007/s11356-015-5319-4. ‌Dogrul, Ahmet, and Tayfun I. Uzbay. “Topical Clonidine Antinociception.” Pain, vol. 111, no. 3, Oct. 2004, pp. 385–91, https://doi.org/10.1016/j.pain.2004.07.020.