| Name: | Clonidine 2,6-Dichloroaniline Impurity |
| Catalogue No. | VL281001 |
| CAS No. | 608-31-1 |
| Molecular Formula | C₆H₅Cl₂N |
| Molecular Weight | 162.02 |
| Status | In-stock |
| IUPAC Name | 2,6-Dichlorobenzenamine |
| Synonyms | Clonidine EP Impurity C |
| Appearance | Off White Crystalline solid |
| Description | Clonidine 2,6-Dichloroaniline Impurity (CAS No: 608-31-1) or 2,6-Dichlorobenzenamine is a pharmaceutical intermediate of Clonidine. Clonidine is an alpha-2 adrenergic agonist which is a significantly potent antinociceptive agent but its use as systemic clonidine for the cure of pain is limited by centrally mediated side effects including sedation, hypotension, and rebound hypertension. |
| References | Lin, Weixiong, et al. “Oxidation of Aniline Aerofloat in Flotation Wastewater by Sodium Hypochlorite Solution.” Environmental Science and Pollution Research, vol. 23, no. 1, Sept. 2015, pp. 785–92, https://doi.org/10.1007/s11356-015-5319-4. Dogrul, Ahmet, and Tayfun I. Uzbay. “Topical Clonidine Antinociception.” Pain, vol. 111, no. 3, Oct. 2004, pp. 385–91, https://doi.org/10.1016/j.pain.2004.07.020. |
