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Clonidine EP impurity A

Clonidine EP impurity A

Catalogue No.: VL281007
CAS No.: 5391-39-9

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Name: Clonidine EP impurity A
Catalogue No. VL281007
CAS No. 5391-39-9
Molecular Formula C5H8N2O2
Molecular Weight 128.13
Status In-stock
IUPAC Name N-Acetyl-2-imidazolidinone
Appearance Off White powder
Description Clonidine EP impurity A (CAS No: 5391-39-9) or N-Acetyl-2-imidazolidinon induces Diastereoselectivity that is majorly dependent on the N-substituents of the heterocycles. This type of reaction depicts the good level of diastereoselection in the methylation of N′-butyryl-2-imidazolidinones through the metal enolates.
References Abdel-Aziz, Alaa A. -M, et al. “An Unusual Enhancement of Chiral Induction by Chiral 2-Imidazolidinone Auxiliaries.” Tetrahedron Letters, vol. 41, no. 44, Oct. 2000, pp. 8533–37, https://doi.org/10.1016/s0040-4039(00)01547-1.

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