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Clonidine Related Compound B

Clonidine Related Compound B

Catalogue No.: VE006800
CAS No.: N/A

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Name: Clonidine Related Compound B
Catalogue No. VE006800
CAS No. N/A
Molecular Formula C20H20Cl4N6
Molecular Weight 486.23
Status In-stock
IUPAC Name 2-[(E)-2,6-Dichlorophenylimino]-1-(1-{2-[(E)-2,6-dichlorophenylimino]-imidazolidin-1-yl}-ethyl) imidazolidine
Description Clonidine Related Compound B or 2-[(E)-2,6-Dichlorophenylimino]-1-(1-{2-[(E)-2,6-dichlorophenylimino]-imidazolidin-1-yl}-ethyl) imidazolidine is a metabolic intermediate of Clonidine. Clonidine is a centrally acting antihypertensive agent potent in the cure of mild, moderate, and severe hypertension, alone or infusing with other drugs. The use of oral clonidine has usually been restricted by side effects which include dry mouth and drowsiness.
References Summers, Roger J., et al. “Displacement of [3H]Clonidine Binding by Clonidine Analogues in Membranes from Rat Cerebral Cortex.” European Journal of Pharmacology, vol. 66, no. 2-3, Aug. 1980, pp. 233–41, https://doi.org/10.1016/0014-2999(80)90147-8. ‌Lowenthal, D. T., et al. “Clinical Pharmacokinetics of Clonidine.” Clinical Pharmacokinetics, vol. 14, no. 5, May 1988, pp. 287–310, https://doi.org/10.2165/00003088-198814050-00002.

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