English
Portuguese
Czech
| Name: | Clorabacavir Racemic |
| Catalogue No. | VL760012 |
| CAS No. | 1918156-05-4 |
| Molecular Formula | C11H12ClN5O : HCl |
| Molecular Weight | 265.70 : 36.46 |
| Status | In-stock |
| IUPAC Name | ((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hydrochloride |
| Description | Clorabacavir Racemic (CAS No: 1918156-05-4) is an impurity formed during the synthesis of Abacavir which is a nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus infection. It acts by inhibiting HIV reverse transcriptase by competing with the endogenous substrate dGTP. |
| References | Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11. |
