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Clorabacavir Racemic

Clorabacavir Racemic

Catalogue No.: VL760012
CAS No.: 1918156-05-4

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Name: Clorabacavir Racemic
Catalogue No. VL760012
CAS No. 1918156-05-4
Molecular Formula C11H12ClN5O : HCl
Molecular Weight 265.70 : 36.46
Status In-stock
IUPAC Name ((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hydrochloride
Description Clorabacavir Racemic (CAS No: 1918156-05-4) is an impurity formed during the synthesis of Abacavir which is a nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus infection. It acts by inhibiting HIV reverse transcriptase by competing with the endogenous substrate dGTP.
References Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.

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