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Clozapine EP Impurity C

Clozapine EP Impurity C

Catalogue No.: VL1310003
CAS No.: 6104-71-8

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Name: Clozapine EP Impurity C
Catalogue No. VL1310003
CAS No. 6104-71-8
Molecular Formula C17H17ClN4
Molecular Weight 312.8
Status In-stock
IUPAC Name 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[B,E][1,4]diazepine;
Synonyms Clozapine BP Impurity C/ N-Desmethyl Clozapine
Appearance Light Yellow to Yellow Solid
Description Clozapine EP Impurity C (CAS No.: 6104-71-8) or N-Desmethyl Clozapine is a metabolite of Clozapine and is useful in patients with schizophrenia. Clozapine has shown superior efficacy in curing positive and negative symptoms in treatment-resistant schizophrenic patient and is known to cause minimal or no extrapyramidalside effects (EPS) and has minor influence on serum prolactin.
References Aravagiri, M., and S. R. Marder. “Simultaneous Determination of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in Plasma by Liquid Chromatography/Electrospray Tandem Mass Spectrometry and Its Application to Plasma Level Monitoring in Schizophrenic Patients.” Journal of Pharmaceutical and Biomedical Analysis, vol. 26, no. 2, Sept. 2001, pp. 301–11,https://doi.org/10.1016/s0731-7085(01)00410-1.‌Miller, Del D. “Review and Management of Clozapine Side Effects.” The Journal of Clinical Psychia

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