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Colchicine EP Impurity C

Colchicine EP Impurity C

Catalogue No.: VL3080006
CAS No.: 6901-13-9

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Name: Colchicine EP Impurity C
Catalogue No. VL3080006
CAS No. 6901-13-9
Molecular Formula C22H25NO6
Molecular Weight C22H25NO6
Status In-stock
IUPAC Name N-[(7S,7bR,10aS)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamideC22H25NO6
Synonyms Colchicine BP Impurity C / β-Lumicolchicine / β-Lumi (-)-Colchicine
Appearance Off-White to Pale Orange Solid
Description Colchicine EP Impurity C (CAS No.: 6901-13-9) or β-β-Lumicolchicine is an isomer of Colchicine. Colchicine metabolic studies showed that the drug leaves the blood fastly and stays in cells for longer periods of time and its toxicity is majorly gastrointestinal and its mechanism of action depended on interference with microtubular subunit protein aggregation.
References “β-Lumicolchicine as a Tool to Elucidate Microtubular Function in Dentinogenesis.” Acta Odontologica Scandinavica, 2021, www.tandfonline.com/doi/abs/10.3109/00016358109162280. ‌Wallace, Stanley L. “Colchicine.” Seminars in Arthritis and Rheumatism, vol. 3, no. 4, June 1974, pp. 369–81, https://doi.org/10.1016/0049-0172(74)90006-7.

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