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Colchicine EP Impurity D

Colchicine EP Impurity D

Catalogue No.: VL3080007
CAS No.: 477-29-2

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Name: Colchicine EP Impurity D
Catalogue No. VL3080007
CAS No. 477-29-2
Molecular Formula C27H33NO11
Molecular Weight 547.55
Status In-stock
IUPAC Name (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide;
Synonyms Colchicoside
Appearance Pale Yellow Solid
Description Colchicine EP Impurity D (CAS No.: 477-29-2) or Colchicoside is glucosylated colchicine that is less harmful to humans than Colchicine. Colchicine depicts its biological effects by attaching to the soluble tubulin heterodimer which is the main part of the microtubule and it shows its action by binding to brain tubulin.
References YOSHIDA, Keiichiro, et al. “Colchicoside in Colchicum Autumnale Bulbs.” Agricultural and Biological Chemistry, vol. 52, no. 2, 1988, pp. 593–94, https://doi.org/10.1271/bbb1961.52.593. ‌Hastie, Susan Bane. “Interactions of Colchicine with Tubulin.” Pharmacology & Therapeutics, vol. 51, no. 3, Jan. 1991, pp. 377–401, https://doi.org/10.1016/0163-7258(91)90067-v.

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