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Colchicine EP Impurity F

Colchicine EP Impurity F

Catalogue No.: VL3080002
CAS No.: 477-27-0

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Name: Colchicine EP Impurity F
Catalogue No. VL3080002
CAS No. 477-27-0
Molecular Formula C₂₁H₂₃NO₆
Molecular Weight 385.41
Status In-stock
IUPAC Name N-[(7S)-5,6,7,9-Tetrahydro-10-hydroxy-1,2,3,-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
Description Colchicine EP Impurity F (CAS No.: 477-27-0) or N-[(7S)-5,6,7,9-Tetrahydro-10-hydroxy-1,2,3,-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide is a metabolite of Colchicine. Colchicine is a tricyclic and lipid-soluble alkaloid having a long terminal half-life (20 to 40 hours) and good bioavailability between 25% to 88%.
References Alkadi, Hourieh, et al. “Colchicine: A Review on Chemical Structure and Clinical Usage.” Infectious Disorders - Drug Targets, vol. 18, no. 2, May 2018, pp. 105–21, https://doi.org/10.2174/1871526517666171017114901. ‌Slobodnick, Anastasia, et al. “Colchicine: Old and New.” The American Journal of Medicine, vol. 128, no. 5, May 2015, pp. 461–70, https://doi.org/10.1016/j.amjmed.2014.12.010.

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