| Name: | Cyclophosphamide Related Compound A |
| Catalogue No. | VL165001 |
| CAS No. | 821-48-7 |
| Molecular Formula | C4H10Cl3N |
| Molecular Weight | 178.49 |
| Status | In-stock |
| IUPAC Name | Bis(2-Chloroethyl)amine hydrochloride ; |
| Description | Cyclophosphamide Related Compound A (CAS No. 821-48-7) or Bis(2-Chloroethyl)amine hydrochloride is synthesized from diethanolamine with thionyl chloride as chlorination agent and chloroform as solvent. Bis(2-Chloroethyl)amine hydrochloride is also evaluated for use in the treatment of giant follicular lymphoma with nitrogen mustard. |
| References | “N-PHOSPHORYLATED NITROGEN MUSTARDS; PREPARATION of 2-CHLOROETHYL- and BIS(2-CHLOROETHYL)-AMIDES with the BENZODIAZAPHOSPHORINONE RING SYSTEM.” Phosphorus, Sulfur, and Silicon and the Related Elements, 2021,www.tandfonline.com/doi/abs/10.1080/10426509708043542.CHAMBERS, BENJAMIN M. “TREATMENT of GIANT FOLLICULAR LYMPHOMA with NITROGEN MUSTARD (METHYL-BIS-[2-CHLOROETHYL] AMINE).” Archives of Ophthalmology, vol. 43, no. 3, Mar. 1950, p. 520,https://doi.org/10.1001/archopht.1950.00910010529012. |
