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Cyclophosphamide Related Compound A

Cyclophosphamide Related Compound A

Catalogue No.: VL165001
CAS No.: 821-48-7

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Name: Cyclophosphamide Related Compound A
Catalogue No. VL165001
CAS No. 821-48-7
Molecular Formula C4H10Cl3N
Molecular Weight 178.49
Status In-stock
IUPAC Name Bis(2-Chloroethyl)amine hydrochloride ;
Description Cyclophosphamide Related Compound A (CAS No. 821-48-7) or Bis(2-Chloroethyl)amine hydrochloride is synthesized from diethanolamine with thionyl chloride as chlorination agent and chloroform as solvent. Bis(2-Chloroethyl)amine hydrochloride is also evaluated for use in the treatment of giant follicular lymphoma with nitrogen mustard.
References “N-PHOSPHORYLATED NITROGEN MUSTARDS; PREPARATION of 2-CHLOROETHYL- and BIS(2-CHLOROETHYL)-AMIDES with the BENZODIAZAPHOSPHORINONE RING SYSTEM.” Phosphorus, Sulfur, and Silicon and the Related Elements, 2021,www.tandfonline.com/doi/abs/10.1080/10426509708043542.‌CHAMBERS, BENJAMIN M. “TREATMENT of GIANT FOLLICULAR LYMPHOMA with NITROGEN MUSTARD (METHYL-BIS-[2-CHLOROETHYL] AMINE).” Archives of Ophthalmology, vol. 43, no. 3, Mar. 1950, p. 520,https://doi.org/10.1001/archopht.1950.00910010529012.‌

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