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Cyclosporine Impurity B

Cyclosporine Impurity B

Catalogue No.: VL1050004
CAS No.: 63775-95-1

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Name: Cyclosporine Impurity B
Catalogue No. VL1050004
CAS No. 63775-95-1
Molecular Formula C₆₁H₁₀₉N₁₁O₁₂
Molecular Weight 1188.58
Status In-stock
IUPAC Name Ala2-cyclosporine;
Description Cyclosporine Impurity B (CAS No.: 63775-95-1) or Ala2-cyclosporine is an analogue of Cyclosporine. Cyclosporine is an immunosuppressive agent evaluated for use in the treatment of different autoimmune diseases. Cyclosporine is evaluated for use in solid organ transplantation, bone marrow transplantation, psoriasis, rheumatoid arthritis, and nephritic syndrome.
References Efimov, S. V., et al. “Comparison of Cyclosporin Variants B–E Based on Their Structural Properties and Activity in Mitochondrial Membranes.” Biochemical and Biophysical Research Communications, vol. 526, no. 4, June 2020, pp. 1054–60,https://doi.org/10.1016/j.bbrc.2020.03.184.‌Robert, Nadège, et al. “Effect of Cyclosporine on Blood Pressure.” Cochrane Database of Systematic Reviews, Jan. 2010,https://doi.org/10.1002/14651858.cd007893.pub2.‌

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