| Name: | Cyclosporine Impurity B |
| Catalogue No. | VL1050004 |
| CAS No. | 63775-95-1 |
| Molecular Formula | C₆₁H₁₀₉N₁₁O₁₂ |
| Molecular Weight | 1188.58 |
| Status | In-stock |
| IUPAC Name | Ala2-cyclosporine; |
| Description | Cyclosporine Impurity B (CAS No.: 63775-95-1) or Ala2-cyclosporine is an analogue of Cyclosporine. Cyclosporine is an immunosuppressive agent evaluated for use in the treatment of different autoimmune diseases. Cyclosporine is evaluated for use in solid organ transplantation, bone marrow transplantation, psoriasis, rheumatoid arthritis, and nephritic syndrome. |
| References | Efimov, S. V., et al. “Comparison of Cyclosporin Variants B–E Based on Their Structural Properties and Activity in Mitochondrial Membranes.” Biochemical and Biophysical Research Communications, vol. 526, no. 4, June 2020, pp. 1054–60,https://doi.org/10.1016/j.bbrc.2020.03.184.Robert, Nadège, et al. “Effect of Cyclosporine on Blood Pressure.” Cochrane Database of Systematic Reviews, Jan. 2010,https://doi.org/10.1002/14651858.cd007893.pub2. |
