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Dabigatran Impurity P

Dabigatran Impurity P

Catalogue No.: VL1760001
CAS No.: 1408238-37-8

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Name: Dabigatran Impurity P
Catalogue No. VL1760001
CAS No. 1408238-37-8
Molecular Formula C₃₂H₃₆N₆O₆
Molecular Weight 600.66
Status In-stock
IUPAC Name 3-(2-(((4-(((Hexyloxy)carbonyl)carbamoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic Acid
Description Dabigatran Impurity P (CAS No.: 1408238-37-8) or 3-(2-(((4-(((Hexyloxy)carbonyl)carbamoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic Acid is an impurity of Dabigatran which is an oral direct thrombin inhibitor and is evaluated for the prevention of stroke in patients having atrial fibrillation.
References Pantović, Jasmina, et al. “Development of Liquid Chromatographic Method for the Analysis of Dabigatran Etexilate Mesilate and Its Ten Impurities Supported by Quality-By-Design Methodology.” Journal of Pharmaceutical and Biomedical Analysis, vol. 111, July 2015, pp. 7–13,https://doi.org/10.1016/j.jpba.2015.03.009.‌Legrand, Matthieu. “The Use of Dabigatran in Elderly Patients.” Archives of Internal Medicine, vol. 171, no. 14, July 2011, p. 1285,https://doi.org/10.1001/archinternmed.2011.314.‌

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