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Dapagliflozin Acetyl Impurity

Dapagliflozin Acetyl Impurity

Catalogue No.: VL1650004
CAS No.: 1632287-34-3

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Name: Dapagliflozin Acetyl Impurity
Catalogue No. VL1650004
CAS No. 1632287-34-3
Molecular Formula C23H27ClO7
Molecular Weight 450.91
Status In-stock
IUPAC Name ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate
Appearance White Solid
Description Dapagliflozin Acetyl Impurity (CAS No.: 1632287-34-3) or ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate is a metabolite of Dapagliflozin. Dapagliflozin is a gliflozin class drug that is evaluated for the treatment of type-2 diabetes. Dapagliflozin goes through rapid metabolism and transforms into various metabolites in humans.
References KARUMANCHI, KISHORE, et al. “Synthesis of Metabolites of Dapagliflozin: An SGLT2 Inhibitor.” Journal of Chemical Sciences, vol. 132, no. 1, Feb. 2020,https://doi.org/10.1007/s12039-020-1747-x.‌

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