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Dapagliflozin Alpha Isomer

Dapagliflozin Alpha Isomer

Catalogue No.: VL1650001
CAS No.: 1373321-04-0

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Name: Dapagliflozin Alpha Isomer
Catalogue No. VL1650001
CAS No. 1373321-04-0
Molecular Formula C21H25ClO6
Molecular Weight 408.87
Status In-stock
IUPAC Name (2R,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;
Appearance Sticky Light Brown
Description Dapagliflozin Alpha Isomer (CAS No.: 1632287-34-3) or ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate is an α-isomer of Dapagliflozin which is a sodium-glucose co-transporter-2 (SGLT2) blocker and has shown potency on renal outcomes majorly in patients having atherosclerotic cardiovascular disease.
References Jayaraman, K., et al. “A Stepwise Strategy Employing Automated Screening and DryLab Modeling for the Development of Robust Methods for Challenging High Performance Liquid Chromatography Separations: A Case Study.” Analytica Chimica Acta, vol. 696, no. 1-2, June 2011, pp. 116–24,https://doi.org/10.1016/j.aca.2011.04.010.‌Mosenzon, Ofri, et al. “Effects of Dapagliflozin on Development and Progression of Kidney Disease in Patients with Type 2 Diabetes: An Analysis from the DECLARE–TIMI 58 Randomise

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