| Name: | Dapagliflozin Methoxy Impurity |
| Catalogue No. | VL1650002 |
| CAS No. | 714269-57-5 |
| Molecular Formula | C22H27ClO7 |
| Molecular Weight | 438.9 |
| Status | In-stock |
| IUPAC Name | (2S,3R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol |
| Appearance | white solid |
| Description | Dapagliflozin Methoxy Impurity (CAS No.: 714269-57-5) or (2S,3R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol is a methoxy group impurity of Dapagliflozin which is a synthetic SGLT-2 blocker and therefore increases renal glucose excretion which then leads to diminished plasma glucose levels. |
| References | Chen, Yanqing, et al. “Isolation and Characterization of Novel Process-Related Impurities in Empagliflozin.” Journal of Pharmaceutical and Biomedical Analysis, vol. 198, May 2021, p. 114001,https://doi.org/10.1016/j.jpba.2021.114001.Anderson, Sarah L. “Dapagliflozin Efficacy and Safety: A Perspective Review.” Therapeutic Advances in Drug Safety, vol. 5, no. 6, Sept. 2014, pp. 242–54,https://doi.org/10.1177/2042098614551938. |
