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Dapagliflozin Tetraacetate

Dapagliflozin Tetraacetate

Catalogue No.: VE006659
CAS No.: 461432-25-7

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Name: Dapagliflozin Tetraacetate
Catalogue No. VE006659
CAS No. 461432-25-7
Molecular Formula C29H33ClO10
Molecular Weight 577.02
Status In-stock
IUPAC Name (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Description Dapagliflozin Tetraacetate (CAS No.: 461432-25-7) or (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate is a biotransformation product of Dapagliflozin which is a sodium-glucose cotransporter 2 blocker dapagliflozin lowered the composite endpoint of cardiovascular death in a large population of patients having type 2 diabetes mellitus.
References Lemaire, Sébastien, and Didier Schils. “Development of Efficient Routes to Access C-Glycosides as SGLT-2 Inhibitors for the Treatment of Type 2 Diabetes.” Topics in Heterocyclic Chemistry, 2015, pp. 29–50,https://doi.org/10.1007/7081_2015_166.‌Kato, Eri T., et al. “Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus.” Circulation, vol. 139, no. 22, May 2019, pp. 2528–36,https://doi.org/10.1161/circulationaha.119.040130.‌

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