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Darifenacin Impurity A

Darifenacin Impurity A

Catalogue No.: VL1530001
CAS No.: 1048979-16-3

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Name: Darifenacin Impurity A
Catalogue No. VL1530001
CAS No. 1048979-16-3
Molecular Formula C28H29NO3
Molecular Weight 427.21
Status In-stock
IUPAC Name (R)-2-(1-(2-(2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetic acid
Synonyms Darifenacin Carboxylic Acid
Description Darifenacin Impurity A (CAS No.: 1048979-16-3) or Darifenacin Carboxylic Acid is an abundant metabolite of Darifenacin. Darifenacin is a selective muscarinic M3-receptor inhibitor that has been evaluated for use in clinical trials in patients with overactive bladder syndrome (OAB) using a controlled-release formulation.
References Nilvebrant, L., et al. “Tolterodine-a New Bladder Selective Muscarinic Receptor Antagonist: Preclinical Pharmacological and Clinical Data.” Life Sciences, vol. 60, no. 13-14, Feb. 1997, pp. 1129–36,https://doi.org/10.1016/s0024-3205(97)00057-x.‌Croom, Katherine F., and Gillian M. Keating. “Darifenacin.” Drugs & Aging, vol. 21, no. 13, 2004, pp. 885–92,https://doi.org/10.2165/00002512-200421130-00005.‌

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