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Desloratadine N-Acetyl Impurity

Desloratadine N-Acetyl Impurity

Catalogue No.: VL41004
CAS No.: 117796-52-8

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Name: Desloratadine N-Acetyl Impurity
Catalogue No. VL41004
CAS No. 117796-52-8
Molecular Formula C21H21ClN2O
Molecular Weight 352.13
Status In-stock
IUPAC Name 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine
Synonyms Loratadine N-Acetyl Impurity
Description Desloratadine N-Acetyl Impurity (CAS No.: 117796-52-8) or 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine is a derivative of Desloratadine and is a neutral compound in this mobile phase. Desloratadine is a nonsedating antihistamine and is evaluated for the treatment of symptoms seen with seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR), and chronic idiopathic urticaria (CIU) in patients aged above 12 years.
References Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52,https://doi.org/10.1016/j.jpba.2009.08.024.‌ Limon, Lynn, and Denise R. Kockler. “Desloratadine: A Nonsedating Antihistamine.” Annals of Pharmacotherapy, vol. 37, no. 2, Feb. 2003, pp. 237–46,https://doi.org/10.1177/106002800303700216.‌

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