| Name: | Desloratadine N-Acetyl Impurity |
| Catalogue No. | VL41004 |
| CAS No. | 117796-52-8 |
| Molecular Formula | C21H21ClN2O |
| Molecular Weight | 352.13 |
| Status | In-stock |
| IUPAC Name | 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine |
| Synonyms | Loratadine N-Acetyl Impurity |
| Description | Desloratadine N-Acetyl Impurity (CAS No.: 117796-52-8) or 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine is a derivative of Desloratadine and is a neutral compound in this mobile phase. Desloratadine is a nonsedating antihistamine and is evaluated for the treatment of symptoms seen with seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR), and chronic idiopathic urticaria (CIU) in patients aged above 12 years. |
| References | Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52,https://doi.org/10.1016/j.jpba.2009.08.024. Limon, Lynn, and Denise R. Kockler. “Desloratadine: A Nonsedating Antihistamine.” Annals of Pharmacotherapy, vol. 37, no. 2, Feb. 2003, pp. 237–46,https://doi.org/10.1177/106002800303700216. |
