| Name: | Desloratadine N Oxide |
| Catalogue No. | VL41002 |
| CAS No. | 169253-26-3 |
| Molecular Formula | C₁₉H₁₉ClN₂O |
| Molecular Weight | 326.82 |
| Status | In-stock |
| IUPAC Name | 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2- b]pyridine 1-Oxide |
| Synonyms | N-Oxide Derivative of Desloratidine |
| Description | Desloratadine N Oxide (CAS No.: 169253-26-3) or 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2- b]pyridine 1-Oxide is an N-Oxide metabolite of Desloratadine which is a potent antihistaminic compound and increasing desloratadine up to 4-fold betters the chronic urticaria symptoms without altering the safety in patients with difficult-to-treat chronic urticaria. |
| References | Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52,https://doi.org/10.1016/j.jpba.2009.08.024.Staevska, Maria, et al. “The Effectiveness of Levocetirizine and Desloratadine in up to 4 Times Conventional Doses in Difficult-To-Treat Urticaria.” Journal of Allergy and Clinical Immunology, vol. |
