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Desloratadine N-Hydroxypiperidine

Desloratadine N-Hydroxypiperidine

Catalogue No.: VL41003
CAS No.: 1193725-73-3

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Name: Desloratadine N-Hydroxypiperidine
Catalogue No. VL41003
CAS No. 1193725-73-3
Molecular Formula C₁₉H₁₉ClN₂O
Molecular Weight 326.82
Status In-stock
IUPAC Name 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-ol
Synonyms N-Hydroxy Derivative of Desloratidine
Description Desloratadine N-Hydroxypiperidine (CAS No.: 1193725-73-3) or N-Hydroxy Derivative of Desloratadine is an N-hydroxy derivative of Desloratadine which is a nonsedating selective H1-antihistamine and is proven to be efficacious and rapidly and safely reduced the symptoms during the treatment of perennial allergic rhinitis.
References “Biotransformation and Bioactivation Reactions of Alicyclic Amines in Drug Molecules.” Drug Metabolism Reviews, 2014,www.tandfonline.com/doi/abs/10.3109/03602532.2014.924962.‌Simons, F. Estelle. R., et al. “Efficacy and Safety of Desloratadine in the Treatment of Perennial Allergic Rhinitis.” Journal of Allergy and Clinical Immunology, vol. 111, no. 3, Mar. 2003, pp. 617–22,https://doi.org/10.1067/mai.2003.168.‌

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