
Name: | Desloratadine N-Hydroxypiperidine |
Catalogue No. | VL41003 |
CAS No. | 1193725-73-3 |
Molecular Formula | C₁₉H₁₉ClN₂O |
Molecular Weight | 326.82 |
Status | In-stock |
IUPAC Name | 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-ol |
Synonyms | N-Hydroxy Derivative of Desloratidine |
Description | Desloratadine N-Hydroxypiperidine (CAS No.: 1193725-73-3) or N-Hydroxy Derivative of Desloratadine is an N-hydroxy derivative of Desloratadine which is a nonsedating selective H1-antihistamine and is proven to be efficacious and rapidly and safely reduced the symptoms during the treatment of perennial allergic rhinitis. |
References | “Biotransformation and Bioactivation Reactions of Alicyclic Amines in Drug Molecules.” Drug Metabolism Reviews, 2014,www.tandfonline.com/doi/abs/10.3109/03602532.2014.924962.Simons, F. Estelle. R., et al. “Efficacy and Safety of Desloratadine in the Treatment of Perennial Allergic Rhinitis.” Journal of Allergy and Clinical Immunology, vol. 111, no. 3, Mar. 2003, pp. 617–22,https://doi.org/10.1067/mai.2003.168. |