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Dexamethasone Acetate EP Impurity C

Dexamethasone Acetate EP Impurity C

Catalogue No.: VL273019
CAS No.: N/A

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Name: Dexamethasone Acetate EP Impurity C
Catalogue No. VL273019
Molecular Formula C24H31FO6
Molecular Weight 434.5
Status In-stock
IUPAC Name 9-fluoro-11β,17β-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
Appearance White Powder
Description Dexamethasone Acetate EP Impurity C or 9-fluoro-11β,17β-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate is a debasement of Dexamethasone. Dexamethasone drug delivery system (DDS) was later developed as a biodegradable intravitreal implant to give a sustained delivery of 700 μg of dexamethasone to the retina and vitreous and is sanctioned by the FDA.
References Dongala, Thirupathi, et al. “Stability Indicating LC Method Development for Hydroxychloroquine Sulfate Impurities as Available for Treatment of COVID-19 and Evaluation of Risk Assessment prior to Method Validation by Quality by Design Approach.” Chromatographia, vol. 83, no. 10, Aug. 2020, pp. 1269–81,https://doi.org/10.1007/s10337-020-03945-5.‌London, Nikolas J. S., et al. “The Dexamethasone Drug Delivery System: Indications and Evidence.” Advances in Therapy, vol. 28, no. 5, Mar. 2011, pp. 351

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