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Dexamethasone EP Impurity C

Dexamethasone EP Impurity C

Catalogue No.: VL273017
CAS No.: 426-17-5

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Name: Dexamethasone EP Impurity C
Catalogue No. VL273017
CAS No. 426-17-5
Molecular Formula C22H31FO5
Molecular Weight 394.48
Status In-stock
IUPAC Name (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Description Dexamethasone EP Impurity C (CAS No.: 426-17-5) or (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one is an adulteration of Dexamethasone which is a extensively evaluated anti-emetic compound. It prominently lowers the occuring of nausea and vomiting post laparoscopic cholecystectomy.
References Dongala, Thirupathi, et al. “Stability Indicating LC Method Development for Hydroxychloroquine Sulfate Impurities as Available for Treatment of COVID-19 and Evaluation of Risk Assessment prior to Method Validation by Quality by Design Approach.” Chromatographia, vol. 83, no. 10, Aug. 2020, pp. 1269–81,https://doi.org/10.1007/s10337-020-03945-5.‌Wang, J. J., et al. “Dexamethasone Reduces Nausea and Vomiting after Laparoscopic Cholecystectomy.” British Journal of Anaesthesia, vol. 83, no. 5, Nov.

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