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Dexamethasone EP Impurity D

Dexamethasone EP Impurity D

Catalogue No.: VL273018
CAS No.: 24916-90-3

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Name: Dexamethasone EP Impurity D
Catalogue No. VL273018
CAS No. 24916-90-3
Molecular Formula C₂₂H₂₈O₅
Molecular Weight 372.45
Status In-stock
IUPAC Name (9β,11β,16α)-9,11-Epoxy-17,21-dihydroxy-16-methyl-pregna-1,4-diene- 3,20- dione
Synonyms Dexamethasone 9,11-β Epoxide
Description Dexamethasone EP impurity D (CAS No: 24916-90-3) or Dexamethasone 9,11-β Epoxide is an intermediate of dexamethasone that is extensively employed in the treatment of inflammation, allergy, and diseases associated with adrenal cortex insufficiency therapies.
References Das, Saibal Kumar, et al. “Improvements in Corticosteroid 21-Acetoxy-17α-Hydroxy-16α-Methyl-Pregna-1,4,9(11)-Triene-3,20-Dione Synthesis and Its Use as Common Intermediate in the Synthesis of Some Impurities Related to Dexamethasone and Mometasone.” Steroids, vol. 148, Aug. 2019, pp. 47–55,https://doi.org/10.1016/j.steroids.2019.04.008.

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