| Name: | Dexamethasone EP Impurity G |
| Catalogue No. | VL273012 |
| CAS No. | 1177-87-3 |
| Molecular Formula | C24H31FO6 |
| Molecular Weight | 434.5 |
| Status | In-stock |
| IUPAC Name | 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,1 |
| Synonyms | Betamethasone Acetate EP Impurity B/ 21-O-Acetyl Dexamethasone/ Dexamethasone Acetate/ Dexamethasone Isonicotinate EP Impurity B |
| Description | Dexamethasone EP Impurity G (CAS No: 1177-87-3) is an impurity present in the industrial synthesis of Dexamethasone. Dexamethasone is a potent synthetic corticosteroid containing anti-inflammatory and immunosuppressive properties. It has been broadly used to treat inflammation, allergy, and diseases related to adrenal cortex insufficiency. |
| References | Xu, Qun. “Incorporating Solid-Phase Extraction into Compendial Procedures for the Determination of Dexamethasone and Impurities in Low-Dose Drug Products.” Journal of Pharmaceutical and Biomedical Analysis, vol. 175, Oct. 2019, p. 112773, https://doi.org/10.1016/j.jpba.2019.07.021. Chen, Quan, et al. “A Validated, Stability-Indicating HPLC Method for the Determination of Dexamethasone Related Substances on Dexamethasone-Coated Drug-Eluting Stents.” Journal of Pharmaceutical and Biomedical Anal |
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