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Dexamethasone EP Impurity H

Dexamethasone EP Impurity H

Catalogue No.: VL273024
CAS No.: 10106-41-9

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Name: Dexamethasone EP Impurity H
Catalogue No. VL273024
CAS No. 10106-41-9
Molecular Formula C24H30O5
Molecular Weight 398.5
Status In-stock
IUPAC Name 2-((8S,10S,13S,14S,16R,17R)-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
Description Dexamethasone EP Impurity H (CAS No.: 10106-41-9) or 2-((8S,10S,13S,14S,16R,17R)-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate is an impurity of Dexamethasone. Early administration of dexamethasone can help to diminish the duration of mechanical ventilation and mortality in patients having moderate-to-severe ARDS.
References Dongala, Thirupathi, et al. “Stability Indicating LC Method Development for Hydroxychloroquine Sulfate Impurities as Available for Treatment of COVID-19 and Evaluation of Risk Assessment prior to Method Validation by Quality by Design Approach.” Chromatographia, vol. 83, no. 10, Aug. 2020, pp. 1269–81,https://doi.org/10.1007/s10337-020-03945-5.‌Villar, Jesús, et al. “Dexamethasone Treatment for the Acute Respiratory Distress Syndrome: A Multicentre, Randomised Controlled Trial.” The Lancet Respi

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