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Dexamethasone Sodium Phosphate Diester

Dexamethasone Sodium Phosphate Diester

Catalogue No.: VE006242
CAS No.: N/A

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Name: Dexamethasone Sodium Phosphate Diester
Catalogue No. VE006242
Molecular Formula C44H56F2O12P : Na
Molecular Weight 868.9
Status In-stock
IUPAC Name Sodium bis(2-((9R,10S,11S,13S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl) Phosphate
Description Dexamethasone Sodium Phosphate Diester or Sodium bis(2-((9R,10S,11S,13S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl) Phosphate is a metabolite of Dexamethasone which is evaluated for use in the treatment of patients with multiple myeloma who have had a relapse after one to three previous therapies.
References Cázares-Delgadillo, J., et al. “Transdermal Iontophoresis of Dexamethasone Sodium Phosphate in Vitro and in Vivo: Effect of Experimental Parameters and Skin Type on Drug Stability and Transport Kinetics.” European Journal of Pharmaceutics and Biopharmaceutics, vol. 75, no. 2, June 2010, pp. 173–78,https://doi.org/10.1016/j.ejpb.2010.03.011.‌Richardson, Paul G., et al. “Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma.” New England Journal of Medicine, vol. 352, no. 24, June 20

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