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Dexamethasone sodium phosphate EP Impurity E

Dexamethasone sodium phosphate EP Impurity E

Catalogue No.: VE006239
CAS No.: N/A

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Name: Dexamethasone sodium phosphate EP Impurity E
Catalogue No. VE006239
CAS No. N/A
Molecular Formula C22H30FO8P
Molecular Weight 472.4
Status In-stock
IUPAC Name ((2S,3R,4aS,4bS,10aS,10bR,11S,12aS)-10b-fluoro-2,11-dihydroxy-3,10a,12a-trimethyl-1,8-dioxo-1,2,3,4,4a,4b,5,6,8,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl)methyl dihydrogen phosphate
Description Dexamethasone sodium phosphate EP Impurity E is a metabolite of Dexamethasone is a drug of choice for treating patients affected by COVID-19 virus and resulted in lowering 28-day mortality amongst the patients receiving invasive mechanical ventilation or oxygen alone at randomization.
References Ishidax, T., et al. “Terpenoids Biotransformation in Mammals III: Biotransformation of α-Pinene, β-Pinene, Pinane, 3-Carene, Carane, Myrcene, and P-Cymene in Rabbits.” Journal of Pharmaceutical Sciences, vol. 70, no. 4, Apr. 1981, pp. 406–15,https://doi.org/10.1002/jps.2600700417.‌“Dexamethasone in Hospitalized Patients with Covid-19.” New England Journal of Medicine, vol. 384, no. 8, Feb. 2021, pp. 693–704,https://doi.org/10.1056/nejmoa2021436.‌

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