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Diacerein EP Impurity C

Diacerein EP Impurity C

Catalogue No.: VL158005
CAS No.: 478-43-3

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Name: Diacerein EP Impurity C
Catalogue No. VL158005
CAS No. 478-43-3
Molecular Formula C15H8O6
Molecular Weight 284.22
Status In-stock
IUPAC Name 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (rhein)
Appearance Yellow color Solid
Description Diacerein EP Impurity C (CAS No.: 478-43-3) or 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (rhein) is an active metabolite of Diacerein which has an excellent potency with a safety profile in osteoarthritis treatment. Anti-inflammatory, antioxidant and anti-apoptosis are some pf the major properties depicted by the drug.
References Zhu, Xiaokang, et al. “Synthesis and Hypoglycemic Activity Evaluation of Rhein Amide Derivatives.” Medicinal Chemistry Research, vol. 22, no. 5, Sept. 2012, pp. 2228–34,https://doi.org/10.1007/s00044-012-0215-7.‌Almezgagi, Maged, et al. “Diacerein: Recent Insight into Pharmacological Activities and Molecular Pathways.” Biomedicine & Pharmacotherapy, vol. 131, Nov. 2020, p. 110594,https://doi.org/10.1016/j.biopha.2020.110594.‌

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