
Name: | Diacerein EP Impurity C |
Catalogue No. | VL158005 |
CAS No. | 478-43-3 |
Molecular Formula | C15H8O6 |
Molecular Weight | 284.22 |
Status | In-stock |
IUPAC Name | 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (rhein) |
Appearance | Yellow color Solid |
Description | Diacerein EP Impurity C (CAS No.: 478-43-3) or 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (rhein) is an active metabolite of Diacerein which has an excellent potency with a safety profile in osteoarthritis treatment. Anti-inflammatory, antioxidant and anti-apoptosis are some pf the major properties depicted by the drug. |
References | Zhu, Xiaokang, et al. “Synthesis and Hypoglycemic Activity Evaluation of Rhein Amide Derivatives.” Medicinal Chemistry Research, vol. 22, no. 5, Sept. 2012, pp. 2228–34,https://doi.org/10.1007/s00044-012-0215-7.Almezgagi, Maged, et al. “Diacerein: Recent Insight into Pharmacological Activities and Molecular Pathways.” Biomedicine & Pharmacotherapy, vol. 131, Nov. 2020, p. 110594,https://doi.org/10.1016/j.biopha.2020.110594. |