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Diacerein EP Impurity H

Diacerein EP Impurity H

Catalogue No.: VL158007
CAS No.: 25395-11-3

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Name: Diacerein EP Impurity H
Catalogue No. VL158007
CAS No. 25395-11-3
Molecular Formula C15H12I3NO4
Molecular Weight 396.35
Status In-stock
IUPAC Name 1,8-Bis(acetyloxy)-3-[(acetyloxy)methyl]-9,10-anthracenedione
Synonyms triacetyl aloe emodin
Appearance Yellow Powder
Description Diacerein EP Impurity H (CAS No.: 25395-11-3) or triacetyl aloe emodin is a triacetyl derivative and a metabolite of the compound Diacerein which is an orally administered drug and is evaluated for the treatment of patients with osteoarthritis. Diacerein is fully biotransformed into rhein prior to reaching the systemic circulation.
References "Liu, Yitong, et al. “Liver Toxicity of Anthraquinones: A Combined in Vitro Cytotoxicity and in Silico Reverse Dosimetry Evaluation.” Food and Chemical Toxicology, vol. 140, June 2020, p. 111313,https://doi.org/10.1016/j.fct.2020.111313.‌ ‌Nicolas, P., et al. “Clinical Pharmacokinetics of Diacerein.” Clinical Pharmacokinetics, vol. 35, no. 5, 1998, pp. 347–59,https://doi.org/10.2165/00003088-199835050-00002."

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