| Name: | Diltiazem EP Impurity H |
| Catalogue No. | VL1080005 |
| CAS No. | 115992-91-1 |
| Molecular Formula | C17H18N2OS |
| Molecular Weight | 330.4 |
| Status | In-stock |
| IUPAC Name | (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one |
| Synonyms | Diltiazem Related Compound H |
| Appearance | Yellow Powder |
| Description | Diltiazem EP Impurity H (CAS No.: 115992-91-1) or Diltiazem Related Compound H is a metabolite of Diltiazem which is a calcium antagonist and helps attenuate the routine lowering in the coronary artery diameter during the first year post-cardiac transplantation and also helps block the development of visually evident coronary artery disease. |
| References | Budriesi, Roberta, et al. “Diltiazem Analogues: The Last Ten Years on Structure Activity Relationships.” Current Medicinal Chemistry, vol. 14, no. 3, Feb. 2007, pp. 279–87,https://doi.org/10.2174/092986707779941122. Schroeder, John S., et al. “A Preliminary Study of Diltiazem in the Prevention of Coronary Artery Disease in Heart-Transplant Recipients.” New England Journal of Medicine, vol. 328, no. 3, Jan. 1993, pp. 164–70,https://doi.org/10.1056/nejm199301213280303. |
![(2S,3R)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one](/public/site/files/site_images/thumb_2s-3r-3-hydroxy-2-4-methoxyphenyl-2-3-dihydrobenzo-b-1-4-thiazepin-4-5h-one90848.png)
