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Diltiazem EP Impurity H

Diltiazem EP Impurity H

Catalogue No.: VL1080005
CAS No.: 115992-91-1

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Name: Diltiazem EP Impurity H
Catalogue No. VL1080005
CAS No. 115992-91-1
Molecular Formula C17H18N2OS
Molecular Weight 330.4
Status In-stock
IUPAC Name (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
Synonyms Diltiazem Related Compound H
Appearance Yellow Powder
Description Diltiazem EP Impurity H (CAS No.: 115992-91-1) or Diltiazem Related Compound H is a metabolite of Diltiazem which is a calcium antagonist and helps attenuate the routine lowering in the coronary artery diameter during the first year post-cardiac transplantation and also helps block the development of visually evident coronary artery disease.
References Budriesi, Roberta, et al. “Diltiazem Analogues: The Last Ten Years on Structure Activity Relationships.” Current Medicinal Chemistry, vol. 14, no. 3, Feb. 2007, pp. 279–87,https://doi.org/10.2174/092986707779941122.‌ Schroeder, John S., et al. “A Preliminary Study of Diltiazem in the Prevention of Coronary Artery Disease in Heart-Transplant Recipients.” New England Journal of Medicine, vol. 328, no. 3, Jan. 1993, pp. 164–70,https://doi.org/10.1056/nejm199301213280303.

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