Donepezil Related Compound A

Donepezil Related Compound A

Catalogue No.: VL173010
CAS No.: 145546-80-1

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Catalogue No. VL173010
CAS No. 145546-80-1
Molecular Formula C₂₄H₂₇NO₃
Molecular Weight 377.48
Status In-stock
IUPAC Name (E)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-Inden-1-one
Synonyms Donepezil Dehydro Impurity / Donepezil Related Compound A
Appearance Orange solid
Description Donepezil Related Compound A or Donepezil Dehydro Impurity (CAS No.: 145546-80-1) is a possible impurity during the synthesis of Donepezil. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor used to increase cortical acetylcholine eventually used to treat mild to moderate dementia in Alzheimer’s disease.
References PubChem. “Donepezil.” @Pubchem, PubChem, 2021, pubchem.ncbi.nlm.nih.gov/compound/donepezil. ‌Krishna Reddy, K. V. S. R., et al. “Identification and Characterization of Potential Impurities of Donepezil.” Journal of Pharmaceutical and Biomedical Analysis, vol. 35, no. 5, Sept. 2004, pp. 1047–58, https://doi.org/10.1016/j.jpba.2004.03.022. ‌

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