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Doxycycline EP Impurity D

Doxycycline EP Impurity D

Catalogue No.: VL159003
CAS No.: 97583-08-9

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Name: Doxycycline EP Impurity D
Catalogue No. VL159003
CAS No. 97583-08-9
Molecular Formula C22H24N2O8
Molecular Weight 444.44
Status 444.44
IUPAC Name (4R,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
Synonyms Doxycycline EP Impurity D / 4-Epi 6-Epi Doxycycline
Description Doxycycline EP Impurity D or Doxycycline EP Impurity D / 4-Epi 6-Epi Doxycycline (CAS No. 97583-08-9) or (4R,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide. It is from second generation Tetracycline class of antibiotics. It ia a synthetic derivative of oxytetracyclinre. Its absorption decreases with the antacids.
References "Smith, Kelly, and James J. Leyden. “Safety of Doxycycline and Minocycline: A Systematic Review.” Clinical Therapeutics, vol. 27, no. 9, Sept. 2005, pp. 1329–42, https://doi.org/10.1016/j.clinthera.2005.09.005. ‌Saivin, S., and G. Houin. “Clinical Pharmacokinetics of Doxycycline and Minocycline.” Clinical Pharmacokinetics, vol. 15, no. 6, Dec. 1988, pp. 355–66, https://doi.org/10.2165/00003088-198815060-00001. ‌"

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