| Name: | Doxycycline EP Impurity F |
| Catalogue No. | VL159002 |
| CAS No. | 122861-53-4 |
| Molecular Formula | C23H25NO8 |
| Molecular Weight | 443.45 |
| Status | In-stock |
| IUPAC Name | 4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy- 6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione |
| Synonyms | 2-Acetyl-2-Decarbamoyldoxycycline |
| Description | Doxycycline EP Impurity F or 2-Acetyl-2-Decarbamoyldoxycycline (CAS No. 122861-53-4) or 4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy- 6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione. It is from second generation Tetracycline class of antibiotics. It ia a synthetic derivative of oxytetracyclinre. Its absorption decreases with the antacids. |
| References | "Smith, Kelly, and James J. Leyden. “Safety of Doxycycline and Minocycline: A Systematic Review.” Clinical Therapeutics, vol. 27, no. 9, Sept. 2005, pp. 1329–42, https://doi.org/10.1016/j.clinthera.2005.09.005. Saivin, S., and G. Houin. “Clinical Pharmacokinetics of Doxycycline and Minocycline.” Clinical Pharmacokinetics, vol. 15, no. 6, Dec. 1988, pp. 355–66, https://doi.org/10.2165/00003088-198815060-00001. " |
