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Doxycycline EP Impurity F

Doxycycline EP Impurity F

Catalogue No.: VL159002
CAS No.: 122861-53-4

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Name: Doxycycline EP Impurity F
Catalogue No. VL159002
CAS No. 122861-53-4
Molecular Formula C23H25NO8
Molecular Weight 443.45
Status In-stock
IUPAC Name 4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy- 6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione
Synonyms 2-Acetyl-2-Decarbamoyldoxycycline
Description Doxycycline EP Impurity F or 2-Acetyl-2-Decarbamoyldoxycycline (CAS No. 122861-53-4) or 4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy- 6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione. It is from second generation Tetracycline class of antibiotics. It ia a synthetic derivative of oxytetracyclinre. Its absorption decreases with the antacids.
References "Smith, Kelly, and James J. Leyden. “Safety of Doxycycline and Minocycline: A Systematic Review.” Clinical Therapeutics, vol. 27, no. 9, Sept. 2005, pp. 1329–42, https://doi.org/10.1016/j.clinthera.2005.09.005. ‌Saivin, S., and G. Houin. “Clinical Pharmacokinetics of Doxycycline and Minocycline.” Clinical Pharmacokinetics, vol. 15, no. 6, Dec. 1988, pp. 355–66, https://doi.org/10.2165/00003088-198815060-00001. ‌"

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