
Name: | Doxylamine EP Impurity A |
Catalogue No. | VL38001 |
CAS No. | 873407-01-3 |
Molecular Formula | C17H22N2O |
Molecular Weight | 270.37 |
Status | In-stock |
IUPAC Name | N,N-dimethyl-2-[1(RS)-1-phenyl-1-(pyridine-4-yl)ethoxy]ethanamine |
Synonyms | Doxylamine Succinate Impurity A |
Appearance | Brown Sticky Mass |
Description | Doxylamine EP Impurity A or Doxylamine Succinate Impurity A (CAS No.873407-01-3) or N,N-dimethyl-2-[1(RS)-1-phenyl-1-(pyridine-4- yl)ethoxy]ethanamine. Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting. |
References | "Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030." |