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Doxylamine EP Impurity A

Doxylamine EP Impurity A

Catalogue No.: VL38001
CAS No.: 873407-01-3

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Name: Doxylamine EP Impurity A
Catalogue No. VL38001
CAS No. 873407-01-3
Molecular Formula C17H22N2O
Molecular Weight 270.37
Status In-stock
IUPAC Name N,N-dimethyl-2-[1(RS)-1-phenyl-1-(pyridine-4-yl)ethoxy]ethanamine
Synonyms Doxylamine Succinate Impurity A
Appearance Brown Sticky Mass
Description Doxylamine EP Impurity A or Doxylamine Succinate Impurity A (CAS No.873407-01-3) or N,N-dimethyl-2-[1(RS)-1-phenyl-1-(pyridine-4- yl)ethoxy]ethanamine. Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting.
References "Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. ‌Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030."

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