
Name: | Doxylamine EP Impurity B (HCl salt) |
Catalogue No. | VE007036 |
CAS No. | 879671-67-7 |
Molecular Formula | C13H13NO.HCl |
Molecular Weight | 235.71 |
Status | In-Stock |
IUPAC Name | (1RS)-1-Phenyl-1-(pyridine-2-yl)ethanol Hydrochloride |
Description | Doxylamine EP Impurity B (HCl salt) (CAS No. 879671-67-7) or (1RS)-1-Phenyl-1-(pyridine-2-yl)ethanol Hydrochloride. Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting. |
References | "Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030. " |