| Name: | Duloxetine EP Impurity B |
| Catalogue No. | VL202002 |
| CAS No. | 116539-55-0 |
| Molecular Formula | C8H13NOS |
| Molecular Weight | 171.26 |
| Status | In-stock |
| IUPAC Name | (S)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol |
| Synonyms | Duloxetine Alcohol |
| Appearance | Orange Color Crystalline solid |
| Description | Duloxetine EP Impurity B (CAS No. 116539-55-0) or (S)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It is used in the treatment of depression, diabetic neuropathic pain, anxiety, fibromyalgia. It is an moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450. |
| References | "Carter, Natalie J., and Paul L. McCormack. “Duloxetine.” CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. Knadler, Mary Pat, et al. “Duloxetine.” Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-000000000-00000." |
