| Name: | Duloxetine EP Impurity F |
| Catalogue No. | VL202004 |
| CAS No. | 959392-22-4 |
| Molecular Formula | C18H19NOS |
| Molecular Weight | 297.41 |
| Status | In-stock |
| IUPAC Name | (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine |
| Synonyms | Duloxetine Related Compound F |
| Appearance | White powder |
| Description | Duloxetine EP Impurity or Duloxetine Related Compound F (CAS No.959392-22-4) or (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It is used in the treatment of depression, diabetic neuropathic pain, anxiety, fibromyalgia. It is an moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450. |
| References | "Carter, Natalie J., and Paul L. McCormack. “Duloxetine.” CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. Knadler, Mary Pat, et al. “Duloxetine.” Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-000000000-00000." |
