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Duloxetine EP Impurity F

Duloxetine EP Impurity F

Catalogue No.: VL202004
CAS No.: 959392-22-4

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Name: Duloxetine EP Impurity F
Catalogue No. VL202004
CAS No. 959392-22-4
Molecular Formula C18H19NOS
Molecular Weight 297.41
Status In-stock
IUPAC Name (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine
Synonyms Duloxetine Related Compound F
Appearance White powder
Description Duloxetine EP Impurity or Duloxetine Related Compound F (CAS No.959392-22-4) or (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It is used in the treatment of depression, diabetic neuropathic pain, anxiety, fibromyalgia. It is an moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450.
References "Carter, Natalie J., and Paul L. McCormack. “Duloxetine.” CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. ‌Knadler, Mary Pat, et al. “Duloxetine.” Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-000000000-00000."

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