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Duloxetine impurity 10

Duloxetine impurity 10

Catalogue No.: VL202020
CAS No.: 13196-35-5

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Name: Duloxetine impurity 10
Catalogue No. VL202020
CAS No. 13196-35-5
Molecular Formula C9H13NOS
Molecular Weight 183.3
Status In-stock
IUPAC Name 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one
Description Duloxetine impurity 10 (CAS No.13196-35-5) or 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It is used in the treatment of depression, diabetic neuropathic pain, anxiety, fibromyalgia. It is an moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450.
References "Knadler, Mary Pat, et al. “Duloxetine.” Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-000000000-00000. Carter, Natalie J., and Paul L. McCormack. “Duloxetine.” CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. ‌"

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