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Duloxetine Related Compound H

Duloxetine Related Compound H

Catalogue No.: VL202013
CAS No.: 199191-66-7

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Name: Duloxetine Related Compound H
Catalogue No. VL202013
CAS No. 199191-66-7
Molecular Formula C₂₂H₂₃NO₄S
Molecular Weight 397.49
Status In-stock
IUPAC Name -[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid
Description Duloxetine Related Compound H (CAS No.199191-66-7) or 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It is used in the treatment of depression, diabetic neuropathic pain, anxiety, fibromyalgia. It is an moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450.
References "Knadler, Mary Pat, et al. “Duloxetine.” Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-000000000-00000. ‌ Carter, Natalie J., and Paul L. McCormack. “Duloxetine.” CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. ‌"

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