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Dutasteride Dihydro Impurity

Dutasteride Dihydro Impurity

Catalogue No.: VL225003
CAS No.: 164656-22-8

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Name: Dutasteride Dihydro Impurity
Catalogue No. VL225003
CAS No. 164656-22-8
Molecular Formula C₂₇H₃₂F₆N₂O₂
Molecular Weight 530.55
Status In-stock
IUPAC Name 17β-N-[2,5-bis (Trifluoromethyl)phenyl] Carbamoyl-4-aza-5α-androstene-3-one
Description Dutasteride Dihydro Impurity (CAS No.164656-22-8) or 17β-N-[2,5-bis (Trifluoromethyl)phenyl] Carbamoyl-4-aza-5α-androstene-3-one). It is an oral synthetic 4-azasteroid and it is a potent selective inhibitor of type-1 and type-2 5-alpha reductase. It is used in the treatment of moderate to severe symptomatic BPH in men with an enlarged prostate.
References Keam, Susan J., and Lesley J. Scott. “Dutasteride.” Drugs, vol. 68, no. 4, 2008, pp. 463–85, https://doi.org/10.2165/00003495-200868040-00008.Nickel, J. Curtis. “Comparison of Clinical Trials with Finasteride and Dutasteride.” Reviews in Urology, vol. 6 Suppl 9, no. Suppl 9, MedReviews, LLC, 2004, pp. S31-9, www.ncbi.nlm.nih.gov/pmc/articles/PMC1472914/.

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