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Dutasteride EP Impurity A

Dutasteride EP Impurity A

Catalogue No.: VL225002
CAS No.: 104239-97-6

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Name: Dutasteride EP Impurity A
Catalogue No. VL225002
CAS No. 104239-97-6
Molecular Formula C9H27NO3
Molecular Weight 317.42
Status In-stock
IUPAC Name (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-o
Synonyms Dutasteride Acid Impurity
Appearance Off White Powder
Description Dutasteride EP Impurity A or Dutasteride Acid Impurity (CAS No.104239-97-6) or (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid. It is an oral synthetic 4-azasteroid and it is a potent selective inhibitor of type-1 and type-2 5-alpha reductase. It is used in the treatment of moderate to severe symptomatic BPH in men with an enlarged prostate.
References Keam, Susan J., and Lesley J. Scott. “Dutasteride.” Drugs, vol. 68, no. 4, 2008, pp. 463–85, https://doi.org/10.2165/00003495-200868040-00008.Nickel, J. Curtis. “Comparison of Clinical Trials with Finasteride and Dutasteride.” Reviews in Urology, vol. 6 Suppl 9, no. Suppl 9, MedReviews, LLC, 2004, pp. S31-9, www.ncbi.nlm.nih.gov/pmc/articles/PMC1472914/.

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