| Name: | Dutasteride EP Impurity D |
| Catalogue No. | VL225016 |
| CAS No. | N/A |
| Molecular Formula | C27H28F6N2O2 |
| Molecular Weight | 526.51 |
| Status | Under Development |
| IUPAC Name | N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1,5-diene-17α-carboxamide |
| Synonyms | Dutasteride 17a-5-ene |
| Description | Dutasteride EP Impurity D or Dutasteride 17a-5-ene or N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1,5-diene-17α-carboxamide. It is an oral synthetic 4-azasteroid and it is a potent selective inhibitor of type-1 and type-2 5-alpha reductase. It is used in the treatment of moderate to severe symptomatic BPH in men with an enlarged prostate. |
| References | Keam, Susan J., and Lesley J. Scott. “Dutasteride.” Drugs, vol. 68, no. 4, 2008, pp. 463–85, https://doi.org/10.2165/00003495-200868040-00008.Nickel, J. Curtis. “Comparison of Clinical Trials with Finasteride and Dutasteride.” Reviews in Urology, vol. 6 Suppl 9, no. Suppl 9, MedReviews, LLC, 2004, pp. S31-9, www.ncbi.nlm.nih.gov/pmc/articles/PMC1472914/. |
