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Dutasteride EP Impurity H

Dutasteride EP Impurity H

Catalogue No.: VE007793
CAS No.: N/A

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Name: Dutasteride EP Impurity H
Catalogue No. VE007793
CAS No. N/A
Molecular Formula C46H55F6N3O4
Molecular Weight 827.94 g/mol
Status Under Development
IUPAC Name N-[2,5-Bis(Trifluoromethyl)phenyl]-3-oxo-4-[3-oxo-4-aza-5α-androst-1-ene-17α-carbonyl]-4-aza-5α-androst-1-ene-17β-carboxamide
Synonyms Dutasteride Dimer 1/ Dutasteride α-Dimer
Description Dutasteride EP Impurity H or Dutasteride Dimer 1/ Dutasteride α-Dimer or N-[2,5-Bis(Trifluoromethyl)phenyl]-3-oxo-4-[3-oxo-4-aza-5α-androst-1-ene-17α-carbonyl]-4-aza-5α-androst-1-ene-17β-carboxamide. It is an oral synthetic 4-azasteroid and it is a potent selective inhibitor of type-1 and type-2 5-alpha reductase. It is used in the treatment of moderate to severe symptomatic BPH in men with an enlarged prosatate.
References "Keam, Susan J., and Lesley J. Scott. “Dutasteride.” Drugs, vol. 68, no. 4, 2008, pp. 463–85, https://doi.org/10.2165/00003495-200868040-00008. ‌Nickel, J. Curtis. “Comparison of Clinical Trials with Finasteride and Dutasteride.” Reviews in Urology, vol. 6 Suppl 9, no. Suppl 9, MedReviews, LLC, 2004, pp. S31-9, www.ncbi.nlm.nih.gov/pmc/articles/PMC1472914/. ‌"

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