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Efavirenz Related Compound B

Efavirenz Related Compound B

Catalogue No.: VL1680003
CAS No.: 440124-96-9

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Name: Efavirenz Related Compound B
Catalogue No. VL1680003
CAS No. 440124-96-9
Molecular Formula C₁₄H₁₁ClF₃NO₂
Molecular Weight 317.69
Status In-stock
IUPAC Name (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one
Synonyms Efavirenz Ethene Analog
Description Efavirenz Related Compound B or Efavirenz IP Impurity B / Efavirenz Ethene Analog / (E)-Dihydro Efavirenz (CAS No.(4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that shows inhibitory action against HIV-1. It is a benzoxazinone and orally active compound.
References "Adkins, Julie C., and Stuart Noble. “Efavirenz.” Drugs, vol. 56, no. 6, 1998, pp. 1055–64, https://doi.org/10.2165/00003495-199856060-00014. ‌Kenedi, Christopher A., and Harold W. Goforth. “A Systematic Review of the Psychiatric Side-Effects of Efavirenz.” AIDS and Behavior, vol. 15, no. 8, Apr. 2011, pp. 1803–18, https://doi.org/10.1007/s10461-011-9939-5. ‌"

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